How Do TB Drugs Interact With HIV Drugs?
How do TB drugs interact with HIV drugs? – In January, 2012, the US Food and Drug Administration (FDA) issued new guidelines on dosing of an HIV medication used to treat people infected with both HIV and tuberculosis (TB) because of a potential interaction between two of the main drugs used to treat each disease. The drug rifampin, used for treating TB, can lower levels of the HIV medicine efavirenz, so the FDA recommended that patients who weigh more than 50 kg (110 pounds) and who are taking both medications should get 30 percent larger doses of efavirenz (an increase from 600 mg to 800 mg). Now, a new analysis by conducted by researchers with the Adult AIDS Clinical Trials Group (ACTG) at the University of California, San Francisco (UCSF) and the San Francisco General Hospital and Trauma Center (SFGH) suggests this recommended dose adjustment may not be necessary, particularly in non-Caucasian populations. As described in a talk at the XIX International AIDS Conference in Washington, DC on Monday, July 23, 2012, the new FDA guidelines were based on several small studies in European TB patients and one in healthy volunteers, indicating a decrease in efavirenz levels with rifampin. The guidelines were also informed by a mathematical model, which showed that increasing efavirenz to 800 mg when given with rifampin would increase levels to those seen on the regular dose of 600 mg. These data may not apply to patients in African and Asian populations because of genetic differences that lead to higher efavirenz levels …
FBI Surveillance Of Occupy Wall Street Detailed
Filed under: drug treatment programs washington dc
Kevin Zeese was one of the founding organizers of Occupy Washington, D.C., which set up camp just blocks from FBI headquarters and the Department of Justice. Zeese told HuffPost that infiltration by law enforcement agents or informants was an issue …
Read more on Huffington Post
DC Week: 'Fiscal Cliff' Bill Cancels Medicare Pay Cut
Filed under: drug treatment programs washington dc
In announcing the approval, the FDA acknowledged the risk, and indicated that it would be noted in a boxed warning on the drug's label. The warning will also highlight a risk of QT prolongation that can lead to potentially fatal cardiac arrhythmias.
Read more on MedPage Today
An indelible mark, Manitobans we lost in 2012
Filed under: drug treatment programs washington dc
Through the ensuing years of drugs and treatment, she began volunteering at CancerCare Manitoba's Look Good Feel Better program. From there she was hired as the coordinator of the new Guardian Angel Caring Room, the home for its wig program, ….. He …
Read more on Winnipeg Free Press